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Fragment Screening

Empowering Drug Discovery with Advanced Fragment Screening

⦾ 50 years of experience in drug discovery

⦾ Tailored Screening Libraries

⦾ Dedicated Support Team

⦾ Comprehensive Data Analysis

Fragment-Based Drug Discovery (FBDD)



Our high-throughput biophysical screening platform utilizes our proprietary fragment libraries. 

Rapidly screen

Thousands of small molecule fragments

Identify and characterize

Hits that can be developed into more potent drug candidates.

Increase the efficiency

Of the lead discovery process by focusing on fragments that show the most promise in early-stage screening.

Nuclear Magnetic Resonance (NMR)

Provide detailed insights into molecular interactions and structures.These techniques are critical for :

Determining binding sites

Essential for understanding the interaction between potential drug candidates and their targets.

Structural elucidation

Which helps in identifying the conformation of molecules and their dynamic properties within biological systems.

1D NMR Experiments

One-Dimensional Nuclear Magnetic Resonance  experiments are designed to provide a straightforward yet profound analysis of molecular structures and dynamics. This method focuses on the measurement of proton environments within a molecule, offering critical insights into hydrogen bonding, molecular conformation, and phase interactions

Rapid Analysis

Quick acquisition times make 1D NMR an ideal choice for initial screening, allowing for fast decision-making in early-stage drug development.

High Sensitivity

Especially useful in identifying and quantifying small organic compounds, even in complex mixtures.


Requires less sample preparation and lower amounts of material, reducing overall research costs.

2D NMR Experiments

Two-Dimensional Nuclear Magnetic Resonance techniques extend the capabilities of traditional NMR by correlating signals between different types of nuclei. This method provides a detailed map of how atoms within a molecule are connected, which is crucial for elucidating complex structures and interactions.

Structural Elucidation

Enables detailed visualization of molecular structures, helping to understand the 3D arrangement of atoms and their chemical environment.

Interaction Mapping

Essential for identifying interaction points within biomolecules, crucial for target-based drug design.

Dynamic Studies

Offers insights into the behavior of molecules under various conditions, supporting the optimization of drug formulations and stability.

Data Delivery and Analysis (uNMR)


Designed for speed and security.

Same-day Delivery

Enables detailed visualization of molecular structures, helping to understand the 3D arrangement of atoms and their chemical environment.

Multiple Channel

Whether through courier, pick-up or our mail-in service, we ensure that your samples are handled with care and returned with the highest quality data.

Ready to Accelerate Drug Discovery?


Fragment Screening Publications


Accelerate Drug Discovery With NMX

50 years of experience in medicinal chemistry to help reduce Time to Market for North-American Biotech and Pharmaceutical Companies.

 Client-focused Research

NMX provides a client-focused experience that puts your research needs at the forefront to ensure your project success.

⦾ Advanced NMR Screening

NMX leverages advanced NMR techniques to analyze small molecule interactions with high precision

⦾ Enhanced Results Relevancy

NMX provides tailored Screening Libraries specifically designed around your target to enhance screening results impact and relevancy.

⦾ Industry-Leading Innovations

Benefit from our continuous innovation and strategic insights to achieve your goals effectively while saving time and reducing costs.

 Interdisciplinary Experts

Leverage our extensive expertise in biophysics and medicinal chemistry to accelerate your drug discovery programs.

⦾ Accelerated Decision-Making Process

Get actionable data insights from reliable and high-quality screening data to make informed decisions swiftly.

Accelerate Your Path to Discovery Today.

Accelerate Your Path to Discovery

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